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ZO-1 is involved in trophoblastic cell differentiation in human placenta

4 Mar 2010

Abstract excerpt

Trophoblastic cell-cell fusion is an essential event required during human placental development. Several membrane proteins have been described to be directly involved in this process, including connexin 43 (Cx43), syncytin 1 (Herv-W env), and syncytin 2 (Herv-FRD env glycoprotein). Recently, zona occludens (ZO) proteins (peripheral membrane proteins associated with tight junctions, adherens junctions, and gap...

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PMID: 20200207
DOI: 10.1152/ajpcell.00484.2008

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