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Article

Molecular cloning and functional characterization of an ATP-binding cassette transporter OtrC from Streptomyces rimosus.

BMC biotechnology - 20 Aug 2012

Yu Lan, Yan Xiangyun, Wang Long, Chu Ju, Zhuang Yingping, Zhang Siliang, Guo Meijin

Abstract excerpt

BACKGROUND: The otrC gene of Streptomyces rimosus was previously annotated as an oxytetracycline (OTC) resistance protein. However, the amino acid sequence analysis of OtrC shows that it is a putative ATP-binding cassette (ABC) transporter with multidrug resistance function. To our knowledge, none of the ABC transporters in S. rimosus have yet been characterized. In this study, we aimed to characterize the...

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Source

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Identifiers

PMID: 22906146
DOI: 10.1186/1472-6750-12-52
PMCID: PMC3533511

Genes

OTC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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