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Article

Genetic instability and strain degeneration in Streptomyces rimosus.

Applied and environmental microbiology - 1 Jul 1993

Gravius B, Bezmalinović T, Hranueli D, Cullum J

Abstract excerpt

During a strain selection program to improve oxytetracycline production in Streptomyces rimosus R6, isolates that showed extreme morphological instability appeared. Propagation via spores gave much higher instability than did propagation via mycelial fragments. Five phenotypic traits were affected: sporulation, pigmentation, colony morphology, oxytetracycline production, and oxytetracycline resistance. The...

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Identifiers

PMID: 8357256
DOI: 10.1128/aem.59.7.2220-2228.1993
PMCID: PMC182261

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Source receipt: pubmed, retrieved 7 Sept 2026.

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