Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Second-line anti-tuberculosis drug concentrations for susceptibility testing in the MODS assay.

The European respiratory journal - 1 May 2013

Fitzwater Sean Patrick, Sechler G Andrew, Jave Oswaldo, Coronel Jorge, Mendoza Alberto, Gilman Robert H, Friedland Jon S, Moore David A J

Abstract excerpt

Multidrug-resistant tuberculosis (TB) threatens TB control worldwide. The microscopic observation drug susceptibility (MODS) assay is a low-cost, high-performance TB diagnostic tool for rapid liquid culture and direct isoniazid and rifampicin drug susceptibility testing (DST). The objective of this study was to explore the potential for extending the MODS assay to rapid second-line DST and to identify critical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antitubercular Agents
Share to Dose-Response Relationship, Drug

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple, Bacterial

Share to Microbial Sensitivity Tests

Share to ROC Curve

Share to Sputum

Share to Tuberculosis, Multidrug-Resistant

Source

Identifiers

PMID: 22903960
DOI: 10.1183/09031936.00059812

Genes

DST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Second-line anti-tuberculosis drug concentrations for susceptibility testing in the MODS assay.PMID 22903960Read ↗

Evaluation of indirect drug susceptibility testing using the MODS assay for the detection of XDR-TB in China.Semantic proximity Read ↗

Rapid detection of drug-resistant Mycobacterium tuberculosis by Modified MODS assay suitable for resource-poor settings.Semantic proximity Read ↗

Direct Determination of Pyrazinamide (PZA) Susceptibility by Sputum Microscopic Observation Drug Susceptibility (MODS) Culture at Neutral pH: the MODS-PZA Assay.Semantic proximity Read ↗

Diagnosis of tuberculosis in a high burden resource limited settingSemantic proximity Read ↗

Quantitative MODS-Wayne assay for rapid detection of pyrazinamide resistance in Mycobacterium tuberculosis from sputum samples.Semantic proximity Read ↗

Quantitative MODS-Wayne Assay for Rapid Detection of Pyrazinamide Resistance in<i>Mycobacterium tuberculosis</i>from Sputum SamplesSemantic proximity Read ↗

Population pharmacokinetics and dose evaluations of linezolid in the treatment of multidrug-resistant tuberculosisSemantic proximity Read ↗

Genotypic Resistance of Pyrazinamide but Not Minimum Inhibitory Concentration Is Associated With Longer Time to Sputum Culture Conversion in Patients With Multidrug-resistant Tuberculosis.Semantic proximity Read ↗

Minimum inhibitory concentration of cycloserine against Mycobacterium tuberculosis using the MGIT 960 system and a proposed critical concentration.Semantic proximity Read ↗

The potential of a multiplex high-throughput molecular assay for early detection of first and second line tuberculosis drug resistance mutations to improve infection control and reduce costs: a decision analytical modeling study.Semantic proximity Read ↗

Determination of Critical Concentration for Drug Susceptibility Testing of Mycobacterium tuberculosis against Para-Aminosalicylic Acid with clinical isolates with thyA, folC and dfrA mutationsSemantic proximity Read ↗

Rapid diagnosis of tuberculosis and multidrug resistance with the microscopic observation drug susceptibility assay in Ecuador.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.