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Article

Minimum inhibitory concentration of cycloserine against Mycobacterium tuberculosis using the MGIT 960 system and a proposed critical concentration.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Aug 2022

Wu Xiao, Shang Yuanyuan, Ren Weicong, Wang Wei, Wang Yufeng, Xue Zhongtan, Li Shanshan, Pang Yu

Abstract excerpt

OBJECTIVES: We aimed to determine the breakpoint of cycloserine (CS) susceptibility in MGIT and to describe the molecular characteristics of CS-resistant Mycobacterium tuberculosis (MTB) isolates. METHODS: A total of 124 MTB isolates were recruited in our analysis. Minimum inhibitory concentration (MIC) was determined using the MGIT system. The mutations of MTB isolates within alr, ddl, ald, and cycA, potentially...

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PMID: 35577251
DOI: 10.1016/j.ijid.2022.05.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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