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Mitochondrial Proteomic Analysis of Cisplatin Resistance in Ovarian Cancer

17 Aug 2012

Abstract excerpt

Epithelial ovarian cancer (EOC) is the leading cause of death among women with gynecologic malignancies and accounts for approximately 6% of cancer deaths among women. Cisplatin and its analogues form the backbone of the most active chemotherapy regimens in advanced EOC; however, development of platinum resistance is common and typically marks a transition in which curing the patient is no longer possible. An...

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PMID: 22900918
DOI: 10.1021/pr300403d

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