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Novel LIPA-Targeted Therapy for Treating Ovarian Cancer

24 Jan 2024

Abstract excerpt

Ovarian cancer (OCa) is the most lethal form of gynecologic cancer, and the tumor heterogeneities at the molecular, cellular, and tissue levels fuel tumor resistance to standard therapies and pose a substantial clinical challenge. Here, we tested the hypothesis that the heightened basal endoplasmic reticulum stress (ERS) observed in OCa represents an exploitable vulnerability and may overcome tumor heterogeneity....

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Share to Autophagy in Disease and Therapy
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38339252
DOI: 10.3390/cancers16030500

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