Article
Mitochondrial performance in heat acclimation--a lesson from ischemia/reperfusion and calcium overload insults in the heart.
American journal of physiology. Regulatory, integrative and comparative physiology - 15 Oct 2012
Assayag Miri, Saada Ann, Gerstenblith Gary, Canaana Haifa, Shlomai Rivka, Horowitz Michal
Abstract excerpt
Long-term heat acclimation (LTHA; 30 days, 34°C) causes phenotypic adaptations that render protection against ischemic/reperfusion insult (I/R, 30 min global ischemia and 40 min reperfusion) via heat acclimation-mediated cross-tolerance (HACT) mechanisms. Short-term acclimation (STHA, 2 days, 34 °C), in contrast, is characterized by cellular perturbations, leading to increased susceptibility to insults. Here, we...
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