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Article

Epistasis network centrality analysis yields pathway replication across two GWAS cohorts for bipolar disorder.

Translational psychiatry - 14 Aug 2012

Pandey A, Davis N A, White B C, Pajewski N M, Savitz J, Drevets W C, McKinney B A

Abstract excerpt

Most pathway and gene-set enrichment methods prioritize genes by their main effect and do not account for variation due to interactions in the pathway. A portion of the presumed missing heritability in genome-wide association studies (GWAS) may be accounted for through gene-gene interactions and additive genetic variability. In this study, we prioritize genes for pathway enrichment in GWAS of bipolar disorder...

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Source

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Identifiers

PMID: 22892719
DOI: 10.1038/tp.2012.80
PMCID: PMC3432194

Genes

ANK3
DGKH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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