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Article

A Genome-Wide Association Study and Complex Network Identify Four Core Hub Genes in Bipolar Disorder.

International journal of molecular sciences - 19 Dec 2017

Xie Zengyan, Yang Xianyan, Deng Xiaoya, Ma Mingyue, Shu Kunxian

Abstract excerpt

Bipolar disorder is a common and severe mental illness with unsolved pathophysiology. A genome-wide association study (GWAS) has been used to find a number of risk genes, but it is difficult for a GWAS to find genes indirectly associated with a disease. To find core hub genes, we introduce a network analysis after the GWAS was conducted. Six thousand four hundred fifty eight single nucleotide polymorphisms (SNPs)...

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PMID: 29257106
DOI: 10.3390/ijms18122763
PMCID: PMC5751362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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