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Article

microRNA-31/factor-inhibiting hypoxia-inducible factor 1 nexus regulates keratinocyte differentiation.

Proceedings of the National Academy of Sciences of the United States of America - 28 Aug 2012

Peng Han, Kaplan Nihal, Hamanaka Robert B, Katsnelson Julia, Blatt Hanz, Yang Wending, Hao Liangliang, Bryar Paul J, Johnson Randall S, Getsios Spiro, Chandel Navdeep S, Lavker Robert M

Abstract excerpt

Notch plays a critical role in the transition from proliferation to differentiation in the epidermis and corneal epithelium. Furthermore, aberrant Notch signaling is a feature of diseases like psoriasis, eczema, nonmelanoma skin cancer, and melanoma where differentiation and proliferation are impaired. Whereas much is known about the downstream events following Notch signaling, factors responsible for negatively...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22891326
DOI: 10.1073/pnas.1111292109
PMCID: PMC3435188

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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