Article

Hypoxia inducible factor-1a promotes trichogenic gene expression in human dermal papilla cells

2022-11-21

Abstract excerpt

Dermal papilla cells (DPCs) play critical roles in hair follicle development, but the underlying mechanisms that contribute to hair regeneration have yet to be elucidated. In this study, we demonstrated that hypoxia-inducible factor-1a (HIF-1a) is suppressed in scalp tissues of androgenetic alopecia patients and potentially associated with hair follicle development. In DPCs, knockdown of HIF-1a was found to attenu...

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Literature Corpus work: 49c3da2d-082c-574e-9e0c-e38504e6b1e3
DOI: 10.21203/rs.3.rs-2263496/v1

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