Article

DNMT1 mediated methylation silences miR-214-3p gene and promotes hair follicle stem cell differentiate into adipogenic lineages

2020-05-07

Abstract excerpt

<h4>Background: </h4> Dysfunction of the DNA methylation was associated with stem cell reprogramming. Moreover, DNA methyltransferase 1 (DNMT1) deficiency was involved in the differentiation of hair follicle stem cell (HFSc), but the molecular mechanisms remain unknown. Methods HFSc from human scalp tissues were isolated and cultured. The oil red O staining was used to detect the adipogenesis. The interaction rel...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d7613d2b-7003-5471-a04b-2797fd2bdd9e
DOI: 10.21203/rs.3.rs-26400/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

DNMT1 mediated methylation silences miR-214-3p gene and promotes hair follicle stem cell differentiate into adipogenic lineagesDOI 10.21203/rs.3.rs-26400/v1Read

DNMT1-mediated methylation inhibits microRNA-214-3p and promotes hair follicle stem cell differentiate into adipogenic lineagesSemantic proximity Read

Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere GoatSemantic proximity Read

OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferasesSemantic proximity Read

Stem cell‐intrinsic mechanisms regulating adult hair follicle homeostasisSemantic proximity Read

Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound HealingSemantic proximity Read

AIMP1-derived peptide secreted from hair follicle stem cells activates dermal papilla cells to promote hair growthSemantic proximity Read

Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1.Semantic proximity Read

Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin.Semantic proximity Read

Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles.Semantic proximity Read

MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway.Semantic proximity Read

The Epigenetic Regulation of Wound HealingSemantic proximity Read

UV irradiation‐induced DNA hypomethylation around WNT1 gene: Implications for solar lentiginesSemantic proximity Read