Article
Evaluation of dihydrofolate reductase and dihydropteroate synthetase genotypes that confer resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum in Haiti.
Malaria journal - 13 Aug 2012
Carter Tamar E, Warner Megan, Mulligan Connie J, Existe Alexander, Victor Yves S, Memnon Gladys, Boncy Jacques, Oscar Roland, Fukuda Mark M, Okech Bernard A
Abstract excerpt
BACKGROUND: Malaria caused by Plasmodium falciparum infects roughly 30,000 individuals in Haiti each year. Haiti has used chloroquine (CQ) as a first-line treatment for malaria for many years and as a result there are concerns that malaria parasites may develop resistance to CQ over time. Therefore it is important to prepare for alternative malaria treatment options should CQ resistance develop. In many other...
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