Article
Survey of Plasmodium falciparum multidrug resistance-1 and chloroquine resistance transporter alleles in Haiti.
Malaria journal - 19 Nov 2013
Elbadry Maha A, Existe Alexandre, Victor Yves S, Memnon Gladys, Fukuda Mark, Dame John B, Yowell Charles A, Okech Bernard A
Abstract excerpt
BACKGROUND: In Haiti where chloroquine (CQ) is widely used for malaria treatment, reports of resistance are scarce. However, recent identification of CQ resistance genotypes in one site is suggestive of an emerging problem. Additional studies are needed to evaluate genetic mutations associated with CQ resistance, especially in the Plasmodium falciparum multi-drug resistance-1 gene (pfmdr1) while expanding the...
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