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Article

Association of BMPR1A polymorphism, but not BMP4, with kidney size in full-term newborns.

Pediatric nephrology (Berlin, Germany) - 1 Mar 2013

Kaczmarczyk Mariusz, Goracy Iwona, Loniewska Beata, Kuprjanowicz Anna, Binczak-Kuleta Agnieszka, Clark Jeremy S, Ciechanowicz Andrzej

Abstract excerpt

BACKGROUND: A correlation between renal mass and nephron number in newborns allows the use of total kidney volume at birth as a surrogate for congenital nephron number. As the bone morphogenetic protein type 4 (BMP4), and its receptor type 1A (BMPR1A, ALK3), play an important role in renal development, we hypothesized that common, functional polymorphisms in their genes might be responsible for variation in...

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Identifiers

PMID: 22886282
DOI: 10.1007/s00467-012-2277-7
PMCID: PMC3555310

Genes

BMP4

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