Article
Genetic variants associated with adult blood pressure and kidney function do not affect fetal kidney volume. The Generation R Study.
Early human development - 1 Sept 2012
Taal H Rob, van den Hil Leontine C L, Hofman Albert, van der Heijden Albert J, Jaddoe Vincent W V
Abstract excerpt
BACKGROUND: Smaller kidneys with reduced number of nephrons in early life lead to impaired kidney function and risk for hypertension and chronic kidney disease. These associations might be partly explained by common genetic variation. AIMS: To assess the associations between common genetic variants, which have recently shown to be associated with blood pressure or kidney function, with fetal kidney volume. STUDY...
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