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Article

A common variant of the PAX2 gene is associated with reduced newborn kidney size.

Journal of the American Society of Nephrology : JASN - 1 Jun 2007

Quinlan Jacklyn, Lemire Mathieu, Hudson Thomas, Qu Huiqi, Benjamin Alice, Roy Anne, Pascuet Elena, Goodyer Meigan, Raju Chandhana, Zhang Zhao, Houghton Fiona, Goodyer Paul

Abstract excerpt

Congenital nephron number ranges widely in the human population. Suboptimal nephron number may be associated with increased risk for essential hypertension and susceptibility to renal injury, but the factors that set nephron number during kidney development are unknown. In renal-coloboma syndrome...

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Share to Gene Expression Regulation, Developmental
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17513325
DOI: 10.1681/ASN.2006101107

Genes

PAX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17513325-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A common variant of the PAX2 gene is associated with reduced newborn kidney size.PMID 17513325Read ↗

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Genetics of renal hypoplasia: insights into the mechanisms controlling nephron endowment.Semantic proximity Read ↗

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