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Article

Sex hormone-binding globulin levels are not causally related to venous thrombosis risk in women not using hormonal contraceptives.

Journal of thrombosis and haemostasis : JTH - 1 Oct 2012

Stegeman B H, Helmerhorst F M, Vos H L, Rosendaal F R, Van Hylckama Vlieg A

Abstract excerpt

BACKGROUND: Oral contraceptive use increases the risk of venous thrombosis as well as sex hormone-binding globulin (SHBG) levels. Furthermore, increased SHBG levels are positively associated with activated protein C (APC) resistance and thrombotic risk in oral contraceptive users. OBJECTIVES: To determine whether increased SHBG levels are causally related to venous thrombosis in women not using hormonal...

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Share to Activated Protein C Resistance
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22882730
DOI: 10.1111/j.1538-7836.2012.04878.x

Genes

SHBG
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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