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Article

DNA methylation: a mechanism for embedding early life experiences in the genome.

Child development - 1 Jan 2000

Szyf Moshe, Bick Johanna

Abstract excerpt

Although epidemiological data provide evidence that early life experience plays a critical role in human development, the mechanism of how this works remains in question. Recent data from human and animal literature suggest that epigenetic changes, such as DNA methylation, are involved not only in cellular differentiation but also in the modulation of genome function in response to early life experience affecting...

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Identifiers

PMID: 22880724
DOI: 10.1111/j.1467-8624.2012.01793.x
PMCID: PMC4039199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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