Article
Genetic variation in the epigenetic machinery and mental health.
Current psychiatry reports - 1 Apr 2012
Murgatroyd Chris, Spengler Dietmar
Abstract excerpt
DNA methylation and chromatin modifications regulate gene expression and contribute to changes in brain transcriptomes underlying neurodevelopmental and psychiatric disorders. Clinical genetics and preclinical animal models highlight the crucial importance of the correct establishment of epigenetic marks during sensitive windows of development for normal brain function. On the same side of the coin, some of the...
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