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Article

Impact of genetic and epigenetic factors from early life to later disease.

Metabolism: clinical and experimental - 1 Oct 2008

Tremblay Johanne, Hamet Pavel

Abstract excerpt

There is ample evidence that subtle changes in the early environment, not restricted to the fetal period but expanded to the plastic phase of early development, influence adulthood disease appearance. There is also evidence that genetic background resulting from our evolution is an important contributor to susceptibility to perinatal imprinting. However, rapid adjustment and optimization, at times necessary for...

Topics

Animals
Child
Child Development
Diabetes Mellitus, Type 2
Epigenesis, Genetic
Female
Fetal Development
Genetic Diseases, Inborn
Genetic Predisposition to Disease
Genomic Imprinting
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Infant

Models, Biological

Pregnancy

Source

Identifiers

PMID: 18803962
DOI: 10.1016/j.metabol.2008.07.012

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