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Article

Successful development of small diameter tissue-engineering vascular vessels by our novel integrally designed pulsatile perfusion-based bioreactor.

PloS one - 1 Jan 2012

Song Lei, Zhou Qiang, Duan Ping, Guo Ping, Li Dianwei, Xu Yuan, Li Songtao, Luo Fei, Zhang Zehua

Abstract excerpt

Small-diameter (<4 mm) vascular constructs are urgently needed for patients requiring replacement of their peripheral vessels. However, successful development of constructs remains a significant challenge. In this study, we successfully developed small-diameter vascular constructs with high patency using our integrally designed computer-controlled bioreactor system. This computer-controlled bioreactor system can...

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Identifiers

PMID: 22880036
DOI: 10.1371/journal.pone.0042569
PMCID: PMC3411804

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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