Article
Identification of key factors in deep O2 cell perfusion for vascular tissue engineering.
The International journal of artificial organs - 1 Jun 2009
Cheema Umber, Hadjipanayi Ektoras, Tammi Noor, Alp Burcak, Mudera Vivek, Brown Robert A
Abstract excerpt
Blood vessel engineering requires an understanding of the parameters governing the survival of resident vascular smooth muscle cells. We have developed an in vitro, collagen-based 3D model of vascular media to examine the correlation of cell density, O2 requirements, and viability. Dense collagen sheets (100 micron) seeded with porcine pulmonary artery smooth muscle cells (PASMCs) at low or high (11.6 or...
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