Article
Cell and tissue responses at the interface with a chitosan hydrogel intended for vascular applications: in vitro and in vivo exploration.
Biomedical materials (Bristol, England) - 30 Jan 2019
Aussel Audrey, Boiziau Claudine, L'Azou Béatrice, Siadous Robin, Delmond Samantha, Montembault Alexandra, David Laurent, Bordenave Laurence, Thébaud Noëlie-Brunehilde
Abstract excerpt
AIMS: The need for small caliber vessels to treat cardiovascular diseases has grown. However, synthetic polymers perform poorly in small-diameter applications. Chitosan hydrogels can provide a novel biological scaffold for vascular engineering. The goal of this study was to explore host cell and tissue behavior at the interface with chitosan-based scaffolds in vitro and in vivo. METHODS AND RESULTS: in vitro, we...
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