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Article

Protective roles of DMP1 in high phosphate homeostasis.

PloS one - 1 Jan 2012

Rangiani Afsaneh, Cao Zhengguo, Sun Yao, Lu Yongbo, Gao Tian, Yuan Baozhi, Rodgers Anika, Qin Chunlin, Kuro-O Makoto, Feng Jian Q

Abstract excerpt

PURPOSE: Dmp1 (dentin matrix protein1) null mice (Dmp1(-/-)) display hypophosphatemic rickets with a sharp increase in fibroblast growth factor 23 (FGF23). Disruption of Klotho (the obligatory co-receptor of FGF23) results in hyperphosphatemia with ectopic calcifications formed in blood vessels a...

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Share to Klotho Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factor-23

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Source

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Identifiers

PMID: 22879941
DOI: 10.1371/journal.pone.0042329
PMCID: PMC3411740

Genes

DMP1
FGF23
PTH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22879941-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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