Article
Metagenomic annotation networks: construction and applications.
PloS one - 1 Jan 2012
Vey Gregory, Moreno-Hagelsieb Gabriel
Abstract excerpt
The derivation and comparison of biological interaction networks are vital for understanding the functional capacity and hierarchical organization of integrated microbial communities. In the current work we present metagenomic annotation networks as a novel taxonomy-free approach for understanding the functional architecture of metagenomes. Specifically, metagenomic operon predictions are exploited to derive...
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