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Article

Modeling the structure and proton transfer pathways of the mutant His-107-Tyr of human carbonic anhydrase II.

Journal of molecular modeling - 1 Jan 2013

Halder Puspita, Taraphder Srabani

Abstract excerpt

We present molecular modeling of the structure and possible proton transfer pathways from the surface of the protein to the zinc-bound water molecule in the active site of the mutant His-107-Tyr of human carbonic anhydrase II (HCAII). No high-resolution structure or crystal structure is available till now for this particular mutant due to its lack of stability at physiological temperature. Our analysis utilizes...

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Identifiers

PMID: 22878862
DOI: 10.1007/s00894-012-1549-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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