Reproductive risk factors in breast cancer and genetic hormonal pathways: a gene-environment interaction in the MCC-Spain project.

doi:10.1186/s12885-018-4182-3

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Reproductive risk factors in breast cancer and genetic hormonal pathways: a gene-environment interaction in the MCC-Spain project.

BMC cancer - 12 Mar 2018

Dierssen-Sotos Trinidad, Palazuelos-Calderón Camilo, Jiménez-Moleón José-Juan, Aragonés Nuria, Altzibar Jone M, Castaño-Vinyals Gemma, Martín-Sanchez Vicente, Gómez-Acebo Inés, Guevara Marcela, Tardón Adonina, Pérez-Gómez Beatriz, Amiano Pilar, Moreno Victor, Molina Antonio J, Alonso-Molero Jéssica, Moreno-Iribas Conchi, Kogevinas Manolis, Pollán Marina, Llorca Javier

Abstract excerpt

BACKGROUND: Reproductive factors are well known risk factors for breast cancer; however, little is known about how genetic variants in hormonal pathways interact with that relationship. METHODS: One thousand one hundred thirty nine cases of breast cancer in women and 1322 frequency-matched controls were compared. Genetic variants in hormonal pathways (identified in the Kyoto Encyclopedia of Genes and Genomes)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Activating Transcription Factor 6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Basic-Leucine Zipper Transcription Factors

Share to Cyclic AMP Response Element-Binding Protein

Share to Hormones

Share to Metabolic Networks and Pathways

Share to Parity

Share to Ribosomal Protein S6 Kinases, 90-kDa

Share to src-Family Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 29530003
DOI: 10.1186/s12885-018-4182-3
PMCID: PMC5848450

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reproductive risk factors in breast cancer and genetic hormonal pathways: a gene-environment interaction in the MCC-Spain project.PMID 29530003Read ↗

Gene-environment interactions for breast cancer risk among Chinese women: a report from the Shanghai Breast Cancer Genetics Study.Semantic proximity Read ↗

Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study.Semantic proximity Read ↗

Gene-environment interactions in breast cancer.Semantic proximity Read ↗

Molecular epidemiology, and possible real-world applications in breast cancer.Semantic proximity Read ↗

Investigating the genetic causal relationship between breast cancer and endometrial cancer: A two-sample Mendelian randomization study.Semantic proximity Read ↗

Reproductive factors and breast cancer risk among BRCA1 or BRCA2 mutation carriers: results from ten studies.Semantic proximity Read ↗

Genetic predisposition, parity, age at first childbirth and risk for breast cancer.Semantic proximity Read ↗

Reproductive factors and familial predisposition for breast cancer by age 50 years. A case-control-family study for assessing main effects and possible gene-environment interaction.Semantic proximity Read ↗

Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors.Semantic proximity Read ↗

Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium.Semantic proximity Read ↗

Body Mass Index and Risk of Female Reproductive System Tumors Subtypes: A Meta-Analysis Using Mendelian Randomization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.