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Article

Concordance of DMET plus genotyping results with those of orthogonal genotyping methods.

Clinical pharmacology and therapeutics - 1 Sept 2012

Fernandez C A, Smith C, Yang W, Lorier R, Crews K R, Kornegay N, Hicks J K, Stewart C F, Kawedia J D, Ramsey L B, Liu C, Evans W E, Relling M V, Broeckel U

Abstract excerpt

There are several hurdles to the clinical implementation of pharmacogenetics. One approach is to employ pre-prescription genotyping, involving interrogation of multiple pharmacogenetic variants using a high-throughput platform. We compared the performance of the Drug Metabolizing Enzymes and Transporters (DMET) Plus array (1,931 variants in 225 genes) with that of orthogonal genotyping methods in 220 pediatric...

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Share to Cytochrome P-450 Enzyme System
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genotyping Techniques

Share to Inactivation, Metabolic

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 22871999
DOI: 10.1038/clpt.2012.95
PMCID: PMC3516299

Genes

DPYD
TPMT
VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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