Article
Assessment of a pharmacogenomic marker panel in a polypharmacy population identified from electronic medical records.
Pharmacogenomics - 1 May 2013
Oetjens Matthew T, Denny Joshua C, Ritchie Marylyn D, Gillani Niloufar B, Richardson Danielle M, Restrepo Nicole A, Pulley Jill M, Dilks Holli H, Basford Melissa A, Bowton Erica, Masys Dan R, Wilke Russell A, Roden Dan M, Crawford Dana C
Abstract excerpt
BACKGROUND: The ADME Core Panel assays 184 variants across 34 pharmacogenes, many of which are difficult to accurately genotype with standard multiplexing methods. METHODS: We genotyped 326 frequently medicated individuals of European descent in Vanderbilt's biorepository linked to de-identified electronic medical records, BioVU, on the ADME Core Panel to assess quality and performance of the assay. We compared...
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