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Article

Targeted Genotyping in Clinical Pharmacogenomics: What Is Missing?

The Journal of molecular diagnostics : JMD - 1 Mar 2022

Lopes Jaime L, Harris Kimberley, Karow Mary Beth, Peterson Sandra E, Kluge Michelle L, Kotzer Katrina E, Lopes Guilherme S, Larson Nicholas B, Bielinski Suzette J, Scherer Steven E, Wang Liewei, Weinshilboum Richard M, Black John L, Moyer Ann M

Abstract excerpt

Clinical pharmacogenomic testing typically uses targeted genotyping, which only detects variants included in the test design and may vary among laboratories. To evaluate the potential patient impact of genotyping compared with sequencing, which can detect common and rare variants, an in silico targeted genotyping panel was developed based on the variants most commonly included in clinical tests and applied to a...

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Identifiers

PMID: 35041929
DOI: 10.1016/j.jmoldx.2021.11.008
PMCID: PMC8961466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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