Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome sequencing as a platform for pharmacogenetic genotyping: a pediatric cohort study

22 May 2017

Abstract excerpt

Abstract Whole-genome sequencing and whole-exome sequencing have proven valuable for diagnosing inherited diseases, particularly in children. However, usage of sequencing data as a pharmacogenetic screening tool to ensure medication safety and effectiveness remains to be explored. Sixty-seven variants in 19 genes with known effects on drug response were compared between genome sequencing and targeted genotyping...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics and Rare Diseases
Share to Pharmaceutical studies and practices
Share to Pharmacogenetics and Drug Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29263831
DOI: 10.1038/s41525-017-0021-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome sequencing as a platform for pharmacogenetic genotyping: a pediatric cohort studyPMID 29263831Read ↗

Comparison of genome sequencing and clinical genotyping for pharmacogenesSemantic proximity Read ↗

Pharmacogenomics in the era of next generation sequencing – from byte to bedsideSemantic proximity Read ↗

Whole genome sequencing in pharmacogenomicsSemantic proximity Read ↗

Assessing the capability of massively parallel sequencing for opportunistic pharmacogenetic screening.Semantic proximity Read ↗

Complete pharmacogenomic profile from exome sequencingSemantic proximity Read ↗

Repurposing of Diagnostic Whole Exome Sequencing Data of 1,583 Individuals for Clinical PharmacogeneticsSemantic proximity Read ↗

Progress towards the integration of pharmacogenomics in practice.Semantic proximity Read ↗

Clinical pharmacogenomic testing and reporting: A technical standard of the American College of Medical Genetics and Genomics (ACMG).Semantic proximity Read ↗

Comprehensive Allele Genotyping in Critical Pharmacogenes Reduces Residual Clinical Risk in Diverse Populations.Semantic proximity Read ↗

Targeted Next-Generation Sequencing for Comprehensive Genetic Profiling of Pharmacogenes.Semantic proximity Read ↗

Benchmarking pharmacogenomics genotyping tools: Performance analysis on short-read sequencing samples and depth-dependent evaluation.Semantic proximity Read ↗

Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequencesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.