Estimating the Frequency of False-Negative Pharmacogenetic Test Results by Self-Reported Ancestry.

Abstract excerpt

Concerns about the applicability of pharmacogenetic (PGx) testing across diverse ancestry groups have risen from the underrepresentation of non-European populations in PGx research. Current PGx panels may fail to detect relevant variants in non-European populations, increasing the likelihood of false-negative results. To investigate this, we assessed reference allele (*1) and genotype (*1/*1) frequencies by...

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• Child
• False Negative Reactions
• Gene Frequency
• Pharmacogenetics
• Pharmacogenomic Testing