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Article

Association of HLA-DR1 with the allergic response to the major mugwort pollen allergen: molecular background.

BMC immunology - 8 Aug 2012

Knapp Bernhard, Fischer Gottfried, Van Hemelen Dries, Fae Ingrid, Maillere Bernard, Ebner Christof, Schreiner Wolfgang, Bohle Barbara, Jahn-Schmid Beatrice

Abstract excerpt

BACKGROUND: Mugwort pollen allergens represent the main cause of pollinosis in late summer. The major allergen, Art v 1, contains only one single immunodominant, solely HLA-DR-restricted T cell epitope (Art v 125-36). The frequency of HLA-DRB1*01 is highly increased in mugwort-allergic individuals and HLA-DR1 serves as restriction element for Art v 125-36. However, Art v 125-36 also binds to HLA-DR4 with high...

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Source

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Identifiers

PMID: 22871092
DOI: 10.1186/1471-2172-13-43
PMCID: PMC3522052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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