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Article

Isothiocyanates from Wasabia japonica activate transient receptor potential ankyrin 1 channel.

Chemical senses - 1 Nov 2012

Uchida Kunitoshi, Miura Yosuke, Nagai Masashi, Tominaga Makoto

Abstract excerpt

6-(Methylsulfinyl)hexyl isothiocyanate (6-MSITC) and 6-(methylthio)hexyl isothiocyanate (6-MTITC) have low pungency and are responsible for the fresh flavor of wasabi (Wasabia japonica [Miq] Matsumura). In this study, we found that these two isothiocyanates activate transient receptor potential ankyrin 1 (TRPA1), and 6-MSITC activates transient receptor potential vanilloid 1 (TRPV1), but not other transient...

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Identifiers

PMID: 22869685
DOI: 10.1093/chemse/bjs065

Genes

TRPA1
TRPV1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Isothiocyanates from Wasabia japonica activate transient receptor potential ankyrin 1 channel.PMID 22869685Read ↗

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