Article
Bone defects in LPA receptor genetically modified mice.
Biochimica et biophysica acta - 1 Jan 2013
Salles Jean Pierre, Laurencin-Dalicieux Sara, Conte-Auriol Françoise, Briand-Mésange Fabienne, Gennero Isabelle
Abstract excerpt
LPA and LPA(1) have been shown to increase osteoblastic proliferation and differentiation as well as activation of osteoclasts. Cell and animal model studies have suggested that LPA is produced by bone cells and bone tissues. We obtained data from invalidated mice which support the hypothesis tha...
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