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Article

Regression based fast multi-trait genome-wide QTL analysis.

Journal of bioinformatics and computational biology - 1 Feb 2021

Alam Md Jahangir, Hossain Md Ripter, Islam S M Shahinul, Mollah Md Nurul Haque

Abstract excerpt

Multivariate simple interval mapping (SIM) is one of the most popular approaches for multiple quantitative trait locus (QTL) analysis. Both maximum likelihood (ML) and least squares (LS) multivariate regression (MVR) are widely used methods for multi-trait SIM. ML-based MVR (MVR-ML) is an expectation maximization (EM) algorithm based iterative and complex time-consuming approach. Although the LS-based MVR...

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PMID: 33472570
DOI: 10.1142/S0219720020500444

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