Article
The intestinal environment of surgical injury transforms Pseudomonas aeruginosa into a discrete hypervirulent morphotype capable of causing lethal peritonitis.
Surgery - 1 Jan 2013
Babrowski Trissa, Romanowski Kathleen, Fink David, Kim Moses, Gopalakrishnan Vissagan, Zaborina Olga, Alverdy John C
Abstract excerpt
BACKGROUND: Secondary peritonitis continues to carry a high mortality rate despite the aggressive use of imaging, drainage, and antibiotics. Although host factors and microbial burden contribute to the outcome of peritonitis, we propose a role for bacterial virulence as a determinant of outcome from peritonitis. Bacterial virulence is an inducible trait that is activated in response to specific local "cues" that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.