Article
HLA-DQ association and allele competition in Chinese narcolepsy.
Tissue antigens - 1 Oct 2012
Han F, Lin L, Li J, Dong S X, An P, Zhao L, Liu N Y, Li Q Y, Yan H, Gao Z C, Faraco J, Strohl K P, Liu X, Miyadera H, Mignot E
Abstract excerpt
In Japanese, Koreans and Caucasians, narcolepsy/hypocretin deficiency is tightly associated with the DRB1*15:01-DQA1*01:02-DQB1*06:02 haplotype. Studies in African-Americans suggest a primary effect of DQB1*06:02, but this observation has been difficult to confirm in other populations because of...
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