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Article

MiR-196a binding-site SNP regulates RAP1A expression contributing to esophageal squamous cell carcinoma risk and metastasis.

Carcinogenesis - 1 Nov 2012

Wang Kai, Li Juan, Guo Hong, Xu Xueqing, Xiong Gang, Guan Xingying, Liu Botao, Li Junxia, Chen Xuedan, Yang Kang, Bai Yun

Abstract excerpt

Polymorphisms in 3' untranslated region (UTR) of cancer-related genes might affect regulation by microRNA (miRNA) and contribute to carcinogenesis. In this study, we screened several single nucleotide polymorphisms (SNPs) in 3'UTR of cancer-related genes and investigated their effects on the risk of esophageal squamous cell carcinoma (ESCC). First, we used SNaPshot assay to genotype seven 3'UTR SNPs in 537 ESCC...

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PMID: 22859270
DOI: 10.1093/carcin/bgs259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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