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Article

Spatio-temporal regulation of ADAR editing during development in porcine neural tissues

27 Jul 2012

Abstract excerpt

Editing by ADAR enzymes is essential for mammalian life. Still, knowledge of the spatio-temporal editing patterns in mammals is limited. By use of 454 amplicon sequencing we examined the editing status of 12 regionally extracted mRNAs from porcine developing brain encompassing a total of 64 putative ADAR editing sites. In total 24 brain tissues, dissected from up to five regions from embryonic gestation day 23,...

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PMID: 22858680
DOI: 10.4161/rna.21082

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