Article
Ablation of retinal horizontal cells from adult mice leads to rod degeneration and remodeling in the outer retina.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Aug 2012
Sonntag Stephan, Dedek Karin, Dorgau Birthe, Schultz Konrad, Schmidt Karl-Friedrich, Cimiotti Kerstin, Weiler Reto, Löwel Siegrid, Willecke Klaus, Janssen-Bienhold Ulrike
Abstract excerpt
In the brain, including the retina, interneurons show an enormous structural and functional diversity. Retinal horizontal cells represent a class of interneurons that form triad synapses with photoreceptors and ON bipolar cells. At this first retinal synapse, horizontal cells modulate signal transmission from photoreceptors to bipolar cells by feedback and feedforward inhibition. To test how the fully developed...
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