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Article

The essential iron-sulfur protein Rli1 is an important target accounting for inhibition of cell growth by reactive oxygen species.

Molecular biology of the cell - 1 Sept 2012

Alhebshi Alawiah, Sideri Theodora C, Holland Sara L, Avery Simon V

Abstract excerpt

Oxidative stress mediated by reactive oxygen species (ROS) is linked to degenerative conditions in humans and damage to an array of cellular components. However, it is unclear which molecular target(s) may be the primary "Achilles' heel" of organisms, accounting for the inhibitory action of ROS. Rli1p (ABCE1) is an essential and highly conserved protein of eukaryotes and archaea that requires notoriously...

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Identifiers

PMID: 22855532
DOI: 10.1091/mbc.E12-05-0413
PMCID: PMC3442406

Genes

ABCE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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