Article
PI3K expression and PIK3CA mutations are related to colorectal cancer metastases.
World journal of gastroenterology - 28 Jul 2012
Zhu Yu-Fen, Yu Bao-Hua, Li Da-Li, Ke Hong-Lin, Guo Xian-Zhi, Xiao Xiu-Ying
Abstract excerpt
AIM: To assess the significance of phosphatidylinositol 3-kinase (PI3K) in colorectal cancer (CRC) and toxicity of LY294002 in CRC cells with different metastatic abilities. METHODS: Sixty formalin-fixed and paraffin-embedded CRC tumor specimens were investigated. Adjacent normal colonic mucosa s...
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