Article
Association of XRCC1 gene single nucleotide polymorphisms and susceptibility to pancreatic cancer in Chinese.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2014
Chen Hongxu, Tang Chun, Liu Menggang, Zhou Bo, Kuang Yi, Yuan Tao, Chen Ping
Abstract excerpt
The human X-ray repair cross-complementing group 1 gene (XRCC1) is an important candidate gene for affecting pancreatic cancer (PC) risk. The objective of this study was to detect whether the c.1471G > A and c.1686C > G polymorphisms of XRCC1 gene influence PC risk. The association of XRCC1 genetic variants with PC risk was analyzed in 328 PC patients and 350 controls by the polymerase chain reaction-restriction...
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