Article
Assessment of alternative genotyping strategies to maximize imputation accuracy at minimal cost.
Genetics, selection, evolution : GSE - 31 Jul 2012
Huang Yijian, Hickey John M, Cleveland Matthew A, Maltecca Christian
Abstract excerpt
BACKGROUND: Commercial breeding programs seek to maximise the rate of genetic gain while minimizing the costs of attaining that gain. Genomic information offers great potential to increase rates of genetic gain but it is expensive to generate. Low-cost genotyping strategies combined with genotype imputation offer dramatically reduced costs. However, both the costs and accuracy of imputation of these strategies...
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