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Article

Detecting disease associated modules and prioritizing active genes based on high throughput data.

BMC bioinformatics - 13 Jan 2010

Qiu Yu-Qing, Zhang Shihua, Zhang Xiang-Sun, Chen Luonan

Abstract excerpt

BACKGROUND: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biological function is not simply controlled by an individual gene since genes function in a cooperative manner to achieve biological processes. In the study of human diseases, rather than to discover disease related genes, identifying disease...

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Identifiers

PMID: 20070902
DOI: 10.1186/1471-2105-11-26
PMCID: PMC2825224

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