Article
A fast and practical approach to genotype phasing and imputation on a pedigree with erroneous and incomplete information.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Pirola Yuri, Della Vedova Gianluca, Biffani Stefano, Stella Alessandra, Bonizzoni Paola
Abstract excerpt
The MINIMUM-RECOMBINANT HAPLOTYPE CONFIGURATION problem (MRHC) has been highly successful in providing a sound combinatorial formulation for the important problem of genotype phasing on pedigrees. Despite several algorithmic advances that have improved the efficiency, its applicability to real da...
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