Article
A linear-time algorithm for reconstructing zero-recombinant haplotype configuration on a pedigree.
BMC bioinformatics - 1 Jan 2012
Lai En-Yu, Wang Wei-Bung, Jiang Tao, Wu Kun-Pin
Abstract excerpt
BACKGROUND: When studying genetic diseases in which genetic variations are passed on to offspring, the ability to distinguish between paternal and maternal alleles is essential. Determining haplotypes from genotype data is called haplotype inference. Most existing computational algorithms for haplotype inference have been designed to use genotype data collected from individuals in the form of a pedigree. A...
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